HGH FRAGMENT 176-191

HGH-Fragment 176-191 is a synthetic peptide fragment derived from the C-terminal region of human growth hormone (amino acids 176–191).
Unlike full-length HGH, this 16-amino-acid fragment selectively influences lipid metabolism without directly affecting insulin-like growth factor 1 (IGF-1) levels or cell proliferation.

In pre-clinical and in-vitro studies, HGH Fragment 176-191 has been shown to stimulate lipolysis (fat breakdown) and inhibit lipogenesis (fat formation), making it a valuable research compound for understanding metabolic regulation, obesity mechanisms, and energy utilization pathways.

Price range: $49.00 through $100.00

$49.00
1 - 2
$39.20 (20% off)
3 - 5
$34.20 (30% off)
6 - 9
$29.40 (40% off)
10+
SKU N/A Category
HGH-Fragment 176-191 is a synthetic peptide fragment derived from the C-terminal region of human growth hormone (amino acids 176–191). Unlike full-length HGH, this 16-amino-acid fragment selectively influences lipid metabolism without directly affecting insulin-like growth factor 1 (IGF-1) levels or cell proliferation. In pre-clinical and in-vitro studies, HGH Fragment 176-191 has been shown to stimulate lipolysis (fat breakdown) and inhibit lipogenesis (fat formation), making it a valuable research compound for understanding metabolic regulation, obesity mechanisms, and energy utilization pathways.
Property
Specification
Peptide Name:
HGH Fragment 176-191
Sequence:
Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Gly-Ser-Cys-Gly-Phe-OH
Amino Acid Length:
16
Molecular Formula:
C₇₈H₁₂₃N₂₃O₂₃S₂
Molecular Weight:
~1817.1 Da
CAS Number:
221231-10-3
Peptide Type:
Human Growth Hormone Fragment (aa 176–191)
Structure Type:
Linear peptide with disulfide bridge (Cys-Cys)
Form:
Lyophilized white / off-white powder
Purity:
99 % (HPLC verified)
Solubility:
Soluble in sterile water or 0.1 % acetic acid for research use
Storage:
−20 °C, protected from light and moisture
Stability:
Stable for 24 months under recommended conditions

Lipolytic and Fat Metabolism Research

  • Selectively binds to adipose tissue cell receptors associated with lipid mobilization.
  • Demonstrated to enhance lipolysis (fat breakdown) and inhibit lipogenesis (fat accumulation) in cell culture and animal models.
  • Provides a research model for studying GH-independent metabolic pathways and fat oxidation mechanisms.

Energy Utilization and Thermogenesis Studies

  • Promotes fatty-acid oxidation and increased cellular energy expenditure through mitochondrial activation pathways.
  • Enables research into energy balance, ATP production, and thermogenic gene expression.
  • Useful for investigating how GH-derived fragments affect cellular metabolic rate without growth hormone side effects.

Glucose Metabolism and Insulin Sensitivity Models

  • Provides data on how GH fragments affect glucose homeostasis, insulin signaling, and energy partitioning.
  • Used to study the distinction between full GH and fragment-specific metabolic effects on carbohydrate metabolism.

Muscle Preservation and Body Composition Research

  • Shown in pre-clinical models to preserve lean muscle mass while reducing adipose tissue accumulation.
  • Offers a controlled platform for studying GH-fragment-induced body composition changes and protein turnover.

Cellular Regeneration and Mitochondrial Efficiency Studies

  • May promote cellular repair by enhancing energy availability and reducing oxidative stress.
  • Serves as a model compound for examining growth factor signaling, AMPK activation, and mitochondrial metabolism.

Peptide Specificity and Safety Profile Research

  • Distinct from full HGH, this fragment lacks pro-proliferative effects associated with insulin or IGF-1 receptor activation.
  • Valuable in comparing targeted GH-fragment actions versus systemic growth hormone activity.

This product is supplied strictly for laboratory research use only. It is not a drug, food, or cosmetic and must not be administered to humans or animals. Proper handling procedures and safety protocols should be followed by trained professionals when working with this material.

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Disclaimer: For Research Use Only

All products and information presented on this website are intended solely for laboratory and scientific research purposes. Nothing contained herein should be interpreted as a recommendation, endorsement, or authorization for human consumption, medical use, or diagnostic application.

Any references to specific peptides, studies, or potential biological functions are provided strictly for informational and educational purposes. Such content must not be considered medical, health, or legal advice, nor encouragement for non-research use.

All compounds are designed for controlled research environments and may be handled only by qualified professionals familiar with appropriate laboratory procedures and regulations. Customers and researchers are urged to consult with scientific, medical, or legal experts before ordering or utilizing any materials.

Revacta Labs promotes the ethical, safe, and lawful study of research-grade materials and expects all users to adhere to applicable local and federal guidelines. This disclaimer applies to all website content, communications, and products offered by Revacta Labs and is subject to change without notice.

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