PT 141
PT-141 (Bremelanotide) is a synthetic heptapeptide derived from the melanocortin peptide family, specifically designed as an analog of α-melanocyte-stimulating hormone (α-MSH). In pre-clinical research, PT-141 is used to study central melanocortin pathways related to neuroendocrine activity, sexual function signaling, vasodilation, behavioral responses, and hypothalamic regulation.
Unlike peripheral vasodilators, PT-141 acts directly through MC3R and MC4R receptor activation within the central nervous system, making it valuable in controlled studies examining arousal signaling, metabolic processes, appetite modulation, and neurohormonal pathways.
$34.00
The following research interests are based on pre-clinical and in-vitro studies only. PT-141 is not approved for human or veterinary use and is supplied exclusively for laboratory research.
Neuroendocrine & Melanocortin Pathway Research
- PT-141 is widely used to investigate MC3R and MC4R activation in central hypothalamic circuits.
- Supports research on neuropeptide signaling, hormonal response, and neuroendocrine regulation.
- Useful in studies exploring neural mechanisms of arousal and behavioral activation.
Sexual Function & Arousal Mechanisms
- Enables study of CNS-mediated arousal pathways independent of peripheral vascular effects.
- Investigated in pre-clinical models for its influence on libido signaling and central melanocortin activation.
- Provides a controlled research tool for examining sexual behavior neurobiology.
Vasodilation & Vascular Response Studies
- Offers a model for studying neurovascular modulation through central receptor pathways.
- Allows examination of blood-flow-related responses via melanocortin stimulation rather than nitric oxide pathways.
- Supports research on cerebrovascular interactions in controlled environments.
Hormonal & Stress-Related Signaling
- Studied for its interactions with neurohormonal networks and hypothalamic signaling cascades.
- Provides insight into peptide-driven hormonal responses and CNS regulatory mechanisms.
- Useful for exploring melanocortin involvement in stress and endocrine modulation.
Metabolic & Appetite Regulation Pathways
- MC4R activity allows research into appetite suppression, caloric intake, and metabolic balance.
- Supports studies on hypothalamic energy regulation and neuropeptide influence on metabolism.
- Contributes to research models analyzing energy expenditure and neural metabolic control.
Inflammatory & Oxidative Stress Studies
- Pre-clinical findings suggest possible roles in cytokine signaling modulation.
- Useful for examining oxidative stress pathways and cellular resilience under experimental conditions.
- Enables investigation into interactions between melanocortin receptors and inflammatory responses.
This product is supplied strictly for laboratory research use only. It is not a drug, food, or cosmetic and must not be administered to humans or animals. Proper handling procedures and safety protocols should be followed by trained professionals when working with this material.
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Disclaimer: For Research Use Only
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