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AOD-9604

AOD-9604

AOD-9604 (Advanced Obesity Drug 9604) is a synthetic peptide fragment derived from the C-terminal region of human growth hormone (hGH). It consists of amino acids 177-191 of the native 191-amino-acid hGH sequence and retains the lipolytic (fat-metabolizing) activity of growth hormone without significantly affecting insulin sensitivity, blood glucose, or cellular proliferation.

Originally developed as a potential anti-obesity agent, AOD-9604 has been widely studied for its ability to stimulate lipolysis (breakdown of stored fat) and inhibit lipogenesis (formation of new fat). Importantly, these effects occur independently of growth hormone receptor activation, making AOD-9604 a powerful and selective research tool for studying fat metabolism, energy regulation, and metabolic signaling without the mitogenic or anabolic effects associated with full-length hGH.

Price range: $45.00 through $64.00

$45.00
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AOD-9604 (Advanced Obesity Drug 9604) is a synthetic peptide fragment derived from the C-terminal region of human growth hormone (hGH). It consists of amino acids 177-191 of the native 191-amino-acid hGH sequence and retains the lipolytic (fat-metabolizing) activity of growth hormone without significantly affecting insulin sensitivity, blood glucose, or cellular proliferation. Originally developed as a potential anti-obesity agent, AOD-9604 has been widely studied for its ability to stimulate lipolysis (breakdown of stored fat) and inhibit lipogenesis (formation of new fat). Importantly, these effects occur independently of growth hormone receptor activation, making AOD-9604 a powerful and selective research tool for studying fat metabolism, energy regulation, and metabolic signaling without the mitogenic or anabolic effects associated with full-length hGH.
Property
Specification
Peptide Name:
AOD-9604
Sequence:
Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Gly-Ser-Cys-Gly-Phe
Length:
15 amino acids
Source:
Amino acids 177–191 of human growth hormone
Molecular Formula:
C₇₂H₁₁₂N₁₈O₂₆S₂
Molecular Weight:
~1815.1 Da
Peptide Type:
Synthetic peptide fragment
Structure Type:
Linear peptide (C-terminal fragment)
Mechanism of Action:
Lipolytic stimulation and lipogenesis inhibition via β-adrenergic and cAMP-dependent pathways
Solubility:
Soluble in water and most physiological buffers

Structural Highlights:

  • Origin: Derived from the C-terminal region of hGH responsible for its metabolic (lipolytic) activity.
  • Selective Action: Retains the fat-metabolizing properties of growth hormone without significantly influencing insulin-like growth factor-1 (IGF-1) levels or cell proliferation.
  • Receptor-Independent: Functions primarily through cAMP-mediated mechanisms rather than direct GH receptor binding.
  • Non-Anabolic Profile: Lacks growth-promoting effects, making it an attractive candidate for targeted metabolic studies.

AOD-9604 is a valuable research tool in the fields of metabolic biology, obesity, adipose tissue regulation, and energy balance. It is widely used in preclinical and experimental studies to investigate mechanisms underlying lipid metabolism and fat homeostasis.

Fat Metabolism & Lipolysis

  • Stimulates the breakdown of stored triglycerides into free fatty acids and glycerol, a process known as lipolysis.
  • Inhibits lipogenesis, preventing the formation of new fat cells and storage of adipose tissue.
  • Promotes fatty acid oxidation and mobilization from adipose depots.

Metabolic Regulation & Energy Balance

  • Enhances metabolic rate and energy expenditure in research models.
  • Supports studies focused on energy homeostasis, nutrient utilization, and body composition dynamics.
  • Does not significantly affect insulin sensitivity or blood glucose regulation, allowing targeted metabolic exploration.

Obesity & Adipocyte Research

  • Investigated as a tool for studying obesity, adipose tissue biology, and lipid storage mechanisms.
  • Useful in exploring how fat distribution and utilization are regulated by peptide signaling pathways.
  • Demonstrates additive or synergistic effects when studied alongside exercise or caloric restriction models.

This product is supplied strictly for laboratory research use only. It is not a drug, food, or cosmetic and must not be administered to humans or animals. Proper handling procedures and safety protocols should be followed by trained professionals when working with this material.

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Disclaimer: For Research Use Only

All products and information presented on this website are intended solely for laboratory and scientific research purposes. Nothing contained herein should be interpreted as a recommendation, endorsement, or authorization for human consumption, medical use, or diagnostic application.

Any references to specific peptides, studies, or potential biological functions are provided strictly for informational and educational purposes. Such content must not be considered medical, health, or legal advice, nor encouragement for non-research use.

All compounds are designed for controlled research environments and may be handled only by qualified professionals familiar with appropriate laboratory procedures and regulations. Customers and researchers are urged to consult with scientific, medical, or legal experts before ordering or utilizing any materials.

Revacta Labs promotes the ethical, safe, and lawful study of research-grade materials and expects all users to adhere to applicable local and federal guidelines. This disclaimer applies to all website content, communications, and products offered by Revacta Labs and is subject to change without notice.

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