HEXARELIN
Hexarelin is a synthetic hexapeptide and potent Growth Hormone Secretagogue (GHS) derived from the GHRP family.
It binds to the ghrelin (GHS-R1a) receptor in the pituitary and hypothalamus, triggering the release of endogenous growth hormone (GH) through calcium-mediated signaling.
Unlike non-selective secretagogues, Hexarelin has been shown in pre-clinical studies to exhibit strong GH-releasing activity, enhanced receptor affinity, and a predictable pulse pattern without significant effects on prolactin or cortisol levels.
It has become a key compound for studying GH axis regulation, IGF-1 signaling, and cellular recovery mechanisms related to muscle growth, tissue repair, and metabolism.
Price range: $45.00 through $60.00
Growth Hormone Secretion and Endocrine Pathway Research
- Acts as a potent agonist of the ghrelin receptor (GHS-R1a), stimulating pituitary somatotrophs to release GH in a dose-dependent manner.
- Used to model GH pulsatility, feedback regulation, and somatotropic axis mechanisms.
- Provides a framework for studying peptide-induced hormonal signaling in endocrine research.
IGF-1 and Anabolic Signaling Mechanisms
- Indirectly elevates IGF-1 (Insulin-Like Growth Factor-1) expression, supporting studies on cell growth, protein synthesis, and regeneration.
- Enables research into PI3K/Akt/mTOR pathway activation and GH-IGF-1 feedback loops.
Muscle and Tissue Regeneration Models
- Enhances myoblast proliferation and tissue recovery in skeletal muscle and connective tissue cultures.
- Often combined with GHRP-2, Ipamorelin, or CJC-1295 in synergy studies of anabolic signaling and recovery kinetics.
- Provides a controlled model for investigating GH-dependent tissue repair and fibroblast activity.
Cardiac and Vascular Function Research
- Used in pre-clinical models to examine cardioprotective and angiogenic pathways.
- Shown to support studies on vascular endothelial function, myocardial cell survival, and peptide-based cardiac regeneration.
Metabolic and Energy Regulation Studies
- Regulates glucose uptake, lipid oxidation, and basal metabolic rate through GH-mediated mechanisms.
- Provides data for research on energy homeostasis, body composition, and metabolic flexibility.
Neuroendocrine and Aging Pathway Research
- Investigated for its potential to stimulate GH secretion in aged or stress-exposed models.
- Useful for studying peptide modulation of neuroendocrine aging, cellular recovery, and hormonal adaptation.
This product is supplied strictly for laboratory research use only. It is not a drug, food, or cosmetic and must not be administered to humans or animals. Proper handling procedures and safety protocols should be followed by trained professionals when working with this material.
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Disclaimer: For Research Use Only
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Any references to specific peptides, studies, or potential biological functions are provided strictly for informational and educational purposes. Such content must not be considered medical, health, or legal advice, nor encouragement for non-research use.
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