IPAMORELIN
Ipamorelin is a synthetic pentapeptide and selective Growth Hormone Secretagogue (GHS) that mimics the natural action of ghrelin on the Growth Hormone Secretagogue Receptor (GHS-R1a). It is part of the GHRP (Growth Hormone Releasing Peptide) family but is distinct for its high receptor selectivity, minimal impact on cortisol and prolactin levels, and stable pharmacokinetic profile.
In pre-clinical and in-vitro research, Ipamorelin has been shown to stimulate growth hormone (GH) release, promote protein synthesis, and enhance recovery and cellular regeneration via activation of GH/IGF-1 signaling pathways. Because of its selective mechanism of action, Ipamorelin serves as an ideal model compound for studying endocrine regulation, muscle and connective tissue regeneration, and metabolic signaling without broad hormonal interference.
Price range: $40.00 through $57.00
Growth Hormone Secretion and Pituitary Research
- Ipamorelin binds selectively to ghrelin (GHS-R1a) receptors in the pituitary and hypothalamus, promoting growth hormone (GH) release through calcium-mediated depolarization.
- Exhibits high receptor specificity with minimal activity on ACTH, cortisol, or prolactin pathways, making it ideal for targeted endocrine studies.
- Provides a model for somatotropic axis regulation and growth hormone pulse frequency investigations.
IGF-1 Signaling and Anabolic Mechanisms
- Indirectly increases hepatic IGF-1 expression, promoting cellular growth, repair, and differentiation.
- Used to explore protein synthesis, myoblast activation, and mTOR signaling in muscle and connective tissue.
- Facilitates study of GH–IGF-1 feedback regulation in endocrine research models.
Muscle Growth and Regeneration Studies
- Promotes myocyte proliferation and tissue remodeling in skeletal muscle research.
- Often combined with CJC-1295 or GRF (1–29) in studies investigating synergistic GH release and muscle hypertrophy mechanisms.
- Enables examination of peptide-driven muscle repair and post-injury regeneration.
Cellular Recovery and Anti-Catabolic Pathways
- Demonstrated in research to reduce proteolysis (protein breakdown) and improve cellular nutrient uptake.
- Provides a foundation for studying anti-catabolic signaling, cellular longevity, and energy metabolism optimization.
- Serves as a model for GH-mediated muscle maintenance under stress or fasting conditions.
Metabolic Regulation and Fat Oxidation Research
- Activates pathways that enhance lipid mobilization and glucose regulation via GH-mediated mechanisms.
- Useful in studies analyzing body composition, fat oxidation, and metabolic rate control.
- Often employed in research models exploring energy balance and thermogenesis.
Bone Density and Tissue Integrity Research
- Provides a model for osteoblast activation and connective tissue growth mediated by GH/IGF-1 pathways.
- Studied for its role in collagen synthesis, joint health, and skeletal structure maintenance in pre-clinical assays.
This product is supplied strictly for laboratory research use only. It is not a drug, food, or cosmetic and must not be administered to humans or animals. Proper handling procedures and safety protocols should be followed by trained professionals when working with this material.
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Disclaimer: For Research Use Only
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Any references to specific peptides, studies, or potential biological functions are provided strictly for informational and educational purposes. Such content must not be considered medical, health, or legal advice, nor encouragement for non-research use.
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