Melanotan 2
Melanotan 2 (MT-II) is a synthetic cyclic heptapeptide designed as an analog of the naturally occurring α-melanocyte-stimulating hormone (α-MSH).
In pre-clinical research, Melanotan 2 has been used to study pathways related to pigmentation, melanocortin receptor signaling, photoprotection, metabolic balance, and neuroendocrine function. Its enhanced structural stability and strong affinity for MC1R–MC5R melanocortin receptors make it a valuable compound for examining melanin synthesis, appetite signaling, energy regulation, and behavioral neurobiology in controlled laboratory settings.
$34.00
The following research interests are based on pre-clinical and in-vitro studies only. Melanotan 2 is not approved for human or veterinary use and is supplied exclusively for laboratory research.
Pigmentation & Melanogenesis Studies
- Melanotan 2 is widely used to investigate MC1R-mediated melanin synthesis and melanocyte activation.
- Supports research on UV-response pathways, melanosome formation, and pigmentation biology.
- Useful in studying eumelanin production and photoprotective signaling mechanisms.
Photoprotection & UV-Damage Research
- Enables study of melanin-driven DNA protection against UV-induced cellular stress.
- Investigated for roles in oxidative stress signaling, free-radical response, and cellular resilience.
- Provides a model for examining melanin’s protective biochemical actions.
Appetite Regulation & Metabolic Signaling
- MC4R activation by Melanotan 2 is used to explore appetite suppression, satiety pathways, and metabolic homeostasis.
- Supports research into energy balance, hypothalamic regulation, and glucose utilization in controlled models.
- Provides insight into neuropeptide systems involved in weight and energy control.
Neuroendocrine & Behavioral Pathways
- Studied for its influence on central melanocortin circuits involved in sexual behavior and neuroendocrine responsiveness.
- Pre-clinical studies explore its role in libido signaling, arousal pathways, and hormonal modulation.
- Useful in research involving MC3R and MC4R neurobehavioral mechanisms.
Inflammation & Oxidative Stress Pathways
- MC receptor activity allows investigation of anti-inflammatory signaling, cytokine modulation, and stress-response pathways.
- Provides insight into oxidative molecular cascades and cellular defense mechanisms.
- Supports research on tissue-level responses to inflammatory stimuli.
Energy Expenditure & Mitochondrial Studies
- Pre-clinical research has examined its impact on energy output, mitochondrial activity, and metabolic rate.
- Useful for exploring cross-talk between melanocortin signaling and cellular energy production.
- Helps characterize receptor-specific pathways related to metabolic activation.
This product is supplied strictly for laboratory research use only. It is not a drug, food, or cosmetic and must not be administered to humans or animals. Proper handling procedures and safety protocols should be followed by trained professionals when working with this material.
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Disclaimer: For Research Use Only
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